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Profhilo is a truly unique treatment to have been introduced in the last 2 years, it is the first BDDE-free injectable product based on hyaluronic acid (HA) and designed to treat skin laxity. Having one of the highest concentrations of this acid on the market (64mg / 2ml) it is boosts, hydrates and remodels the aged and sagging tissue of the skin.

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Profhilo is developed by using a patented technology resulting in hybrid of complexes between high molecular weight HA and low molecular HA without the use of any chemical cross-linking compounds unlike other dermal fillers. These complexes increase the stability of HA to enzymatic and mechanical degradation.

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As a stabilised product Profhilo lasts in the skin around 28 days. During this time the stimulation of 4 different types of collagen and elastin takes place by slow release of HA.

The stimulation results in significant tissue improvement. Therefore Profhilo is much more than a skin booster as it also has a significant tightening / lifting effect on the tissue and it has the ability to bioremodel collagen.

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At Faciem Dermatology London, we are proud to offer PROFHILO treatments on their own or in combination with other aesthetics treatments.

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In Profhilo, the light HA is released slowly from the HA hybrid complexes and therefore does not trigger the first inflammatory chemicals making it very compatible with the body. It also increases patient comfort during and after treatment and provides hydration to the skin especially in the epidermis – the Hydro effect.

Heavy-HA in Profhilo provides a stable HA architecture in the dermis. This gives a volumetric lift effect.

It is thought that combining these two types of HAs increases the type I and type III collagen in fibroblasts ( the cell in the dermis which produces your collagen) and type IV and VII collagen in keratinocytes in the epidermis.

This results in improved skin quality and skin hydration both in the dermis and epidermis. There is also increased production of endogenous HA and elastin giving the skin a more youthful look. The results are really outstanding.